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Ecobank Partners with Code 14 Labs to Enhance Digital Training for Students

Ecobank Partners with Code 14 Labs to Enhance Digital Training for Students

Lagos, February 23, 2025 – Ecobank Nigeria, a subsidiary of Ecobank Group, has teamed up with Code 14 Labs to expand the accessibility and reach of coding education for children across Nigeria. The partnership leverages Code 14 Labs’ interactive coding workbooks, including the “Andrew Teaches” coding workbook, along with its network of trained teachers, to offer affordable annual training and proficiency certification to students.

 

As part of this collaboration, Ecobank will provide nationwide and pan-African access to coding education, utilizing its extensive operational network across the continent. In turn, Code 14 Labs will supply its educational technology and trusted community to ensure high-quality teaching that delivers tangible learning outcomes for students and reassurance for parents.

 

Parents and guardians wishing to have their wards participate in the program are encouraged to open Ecobank’s MyFirst Account—a specialized high yield savings product designed for children under 16.

 

At the signing of the Memorandum of Understanding (MoU) in Lagos, Aeola Ogunyemi, Head of Consumer Banking at Ecobank Nigeria, emphasized that the partnership reflects the bank’s commitment to bridging the digital divide, promoting inclusion, and preparing the next generation for a tech-driven future. She also highlighted how the collaboration aligns with Ecobank’s mission to equip children with the skills necessary to thrive in an increasingly digital world.

 

Adeola Ogunyemi, represented by Victor Yalokwu, Head of Consumer Products & Segments, further explained, “At Ecobank, we recognize that financial literacy and digital education are intertwined. This belief led to the creation of the MyFirst Account, a product aimed at children under 16 to encourage smart financial habits from an early age. By introducing students to coding through Code 14’s innovative mobile app, we’re not just teaching coding skills, but also nurturing problem-solving abilities, creativity, and digital confidence.”

 

Otaru Daudu, Executive Director of Research and Technology at Code 14 Labs, praised the partnership and expressed confidence that, with the support of additional partners like the British Council and the Teachers Registration Council of Nigeria (TRCN), they will achieve their goal of training 50,000 learners to proficiency level in HyperText Markup Language (HTML) and Cascading Style Sheets (CSS), essential programming languages for global internet communication.

Daudu emphasized that Code 14 Labs is committed to scaling critical education components through technology-driven inclusion.

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  • Pain For Gain: Is Your Anavar Cycle Worth It?

    **Pain For Gain: Is Your Anavar Cycle Worth It?**

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    from a medical professional are essential to mitigate these risks.

    ### **Top Secrets: Anavar Before and After Results Explained**

    Results from an Anavar cycle can vary widely depending on the
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    Anavar can stay in the system for up to four weeks after cessation due to its half-life.

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    – **The Basics: How to Take Anavar**
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  • This intake was considered as a part of their normal diet and was accounted for in evaluation of dietary
    consumption. In a post-stroke muscle loss mouse mannequin,
    PINTA-745 demonstrated a big increase in muscle mass, energy, and motor operate [68].
    MSTN’s relationship with muscle progress has led to the widespread
    examine of its inhibition for the therapy of muscle, bone, and metabolic illnesses, in addition to enhancing agricultural meat manufacturing [8–11].
    Scientific trials using MSTN inhibitors began in the early 2000s,
    primarily aiming to increase muscular function and survivability in muscular dystrophies.
    Despite achieving widespread success in preliminary animal trials, the journey to marketplace for MSTN-based medication has been largely disappointing, as not one of the clinically examined inhibitors have been approved for mediating muscle mass [12–14].
    Although the clinical failures of muscular dystrophy-targeting drugs have branded MSTN inhibitors as a fruitless endeavor, latest developments in inhibitor
    utility and design provide promising prospects for developing viable MSTN therapeutics.

    The concern with MYO-X was that it simply didn’t seem
    to translate to more muscle in real-world observational
    studies. Technically there’s four supplements I’ll
    speak about right here, and although there’ll undoubtedly be extra to return in the future, these are of particular relevance to this discussion. Male and feminine bodybuilders can get huge,
    however the elite professionals of the heaviest weight class
    usually keep inside a quantity of pounds
    of one another at their peak. By No Means delay or disregard in search of skilled medical recommendation from your physician or one
    other qualified healthcare supplier because of something you’ve learn on SelfHacked.
    We perceive that studying particular person, real-life experiences is often a
    helpful resource, but it’s never an various alternative to professional medical recommendation, diagnosis,
    or treatment from a professional healthcare supplier. Our science
    staff is put through the strictest vetting course of within the health industry and we frequently reject applicants
    who’ve written articles for most of the largest well being websites which are
    deemed trustworthy. Our science group must move long
    technical science exams, troublesome logical reasoning and studying comprehension checks.

    General, Rg values for all of the complexes have been found to be in vary and
    few fluctuations were noticed, indicating all three complexes maintained compact constructions.
    Thus, MD results confirmed all three complexes had been steady throughout
    the simulation period. PPIs play a significant function in mediating various cellular processes, and thus,
    have attracted research consideration (Guo et al., 2014;
    Qiu et al., 2020). The development within the subject of third-dimensional construction predictions of proteins and
    PPI consists of the current discovery of AlphaFold (Jumper et al., 2021) and AlphaFold2
    (Bryant et al., 2022). Research have proven that PPI offers a means of successfully regulating numerous pathways and of
    growing therapeutic targets. Nonetheless, all the interfaces of proteins don’t contribute equally to PPI (Guo et al., 2014).

    The use, distribution or replica in other forums is permitted, supplied the original author(s)
    and the copyright owner(s) are credited and
    that the original publication in this journal
    is cited, in accordance with accepted educational apply.

    No use, distribution or copy is permitted which does not comply with these terms.
    Get unique well being suggestions, early entry to new products, and
    special discounts—straight to your inbox.
    Dietary Supplements like epicatechin and quercetin may complement your
    efforts but aren’t miraculous solutions. No single technique, including drugs, could be considered one of the
    only ways to inhibit myostatin universally.
    As opposed to myofibrillar hypertrophy, which will increase the actual size and number of the muscle fibres, and is everlasting.
    As a result of this lower in collagen, Welle famous that the mice’s tendons (tissues that
    attach bone to muscle) grew to become increasingly brittle.
    He observed that the mice had a reduction in collagen, a protein needed for
    your physique to keep tendons/bones/ligaments strong.

    Using Myostatin inhibitor dietary supplements to lower your myostatin is similar
    to utilizing testosterone boosters to get the same results from utilizing steroids.
    To overcome these points, have the authors considered evaluating myostatin transcript and protein ranges from muscle
    biopsies? Normality of knowledge was assessed by the Shapiro-Wilk take
    a look at and visible inspection of Q-Q plots.
    Work together with your healthcare professional to slowly and
    safely lower your dose over time so you presumably can cease the medication safely.
    Anybody taking an antidepressant should be watched carefully for worsening melancholy or
    unusual conduct. If you or somebody you know has suicidal
    thoughts when taking an antidepressant, call your healthcare
    professional immediately or get emergency assist.
    Ask your healthcare skilled or pharmacist about the most common attainable unwanted facet effects for
    your particular medication. Serotonin and norepinephrine reuptake inhibitors, additionally known as SNRIs, are a class of medicines which are
    effective in treating melancholy.
    If you don’t want to go the peptide and supplement route,
    you should use natural dietary interventions and way of life changes to cut back myostatin expression. Keep In Mind, supplements alone won’t do the trick—physical exercise and good dietary decisions are simply as important.
    This article hopefully will emphasise that bodybuilding is a journey with yourself.
    I want to see a examine accomplished on a bunch of hardgainers lifting
    weights three times a week and Flex Wheeler just LOOKING at dumbbells thrice per week.
    In regard to his genetics for constructing muscle, Flex Wheeler is simply a phenomenon.
    Myostatin and activins (A and B) bind to the ActRIIA or
    ActRIIB receptor on the cell membrane and may signal through it.
    Inhibition of muscle hypertrophy and differentiation by myostatin happens through Smad2/3 phosphorylation-dependent
    blockade of the AKT-mTOR pathway [180]. So that the therapy of muscle with myostatin or
    activin leads to a lower in the stage of phosphorylated AKT.
    Easy blocking of myostatin was one of many first
    and most blatant therapeutic strategies to appropriate
    muscle atrophy. Because clear hypertrophy was seen in myostatin-null animals and in people who had
    been null for this ligand. Nonetheless, the extent of myostatin reported
    in people is decrease than the level noticed in rodents.
    Therefore, it is affordable to ask the query that
    blocking myostatin alone could be efficient or that we
    should seek to inhibit different ligands that play a role
    in the negative regulation of muscle mass by sending indicators by way of the same receptor.

    Resistance training and regular moderate-intensity
    cardio train are confirmed effective pure methods for potentially decreasing
    myostatin levels and supporting muscle progress. While some drugs and dietary supplements declare
    to affect myostatin levels, their precise influence alone on muscle progress should be considered
    with a wholesome dose of skepticism. If you are dedicated to constructing
    lean muscle mass, you may realize it takes much effort—hours at
    the health club and a protein-rich food plan are
    normally the recipe. However for these who have already dialed of
    their workout routines and vitamin and are in search
    of an extra edge, understanding how myostatin inhibitors work would possibly help you attain the next step in achieving those fitness targets.
    Epi 2.zero by Vital Alchemy presents a focused method to enhancing
    muscle growth by inhibiting myostatin, facilitating improved muscle
    size and power. Quercetin is a flavonoid that acts as a powerful
    antioxidant and also has potential myostatin inhibiting properties.
    It supports endurance and performance by enhancing blood move and reducing inflammation.
    It Is a half of a superfamily of proteins called remodeling development factor-beta
    (TGF-beta), which regulates cell growth and differentiation in each muscular tissues and other tissues.

    Leucine, HMB and creatine most likely all increase muscle progress as a outcome
    of they reduce the functioning of myostatin, the protein that causes
    muscles to atrophy. Molecular scientists at Auburn College within the US write about
    it in the Journal of the International Society of Sports Activities
    Diet. The researchers did in-vitro studies on the effects of leucine,
    HMB and creatine on muscle cells. The physique produces barely
    more myostatin as we age from our 30s to late 50s, making
    it tougher to build muscle mass [12]. Therefore, myostatin inhibitors
    have been an emphasis of analysis regarding sarcopenia (age-related muscle wasting), muscular dystrophy, and other musculoskeletal conditions.
    Notably, the variations in outcomes stem from the differing
    protein consumptions across the studies.
    Likewise, FST has additionally been proven to bind to GDF11, activins A, B, AB, and E, inhibins
    A and B, BMPs 2, 4, 6, 7, and 15 [21, 94]. Muramatsu et al.

    demonstrated the importance of specificity in design by utilizing GYM-329, an antibody which
    particularly targets the latent form of MSTN.
    In mice, GYM-329 was shown to extend muscle mass in 3 different models of muscle dystrophy,
    demonstrating a larger enhance in muscle mass and grip
    strength in comparability with landogrozumab and
    domagrozumab, two unspecific-antibodies [61].
    GYM-329 treatment also resulted in higher grip strength increases over bimagrumab,
    the anti-ActRIIA/B antibody [61]. Focusing On the latent MSTN complicated is in all probability going extra environment friendly not only as a outcome of specificity but also due to the elevated temporal availability of the latent advanced compared to
    the energetic mature dimer [20]. In addition to efficacy issues,
    cross-reactivity poses a serious danger of unwanted effects.

    Adipogenic differentiation was noticed measuring Oil Pink O intensities of control and knockdown cells.
    Oil Purple O intensities have been considerably elevated
    in FMOD knockdown cells (FMODkd, 17%) in contrast with wild-type cells (FMODwt).
    CD36, PPARγ, and MSTN gene expression had been upregulated in FMODkd, while CD36, PPARγ, and FMOD expression were
    downregulated in MSTN knockdown cells (Supplementary Figures S10 and S11A).
    In addition, CD36, PPARγ, and FMOD gene expression in MSTN knockout fats tissues were considerably decrease than in wild-type fats
    (controls) (Supplementary Determine S11B).
    There are quite lots of open supply and licensed virtual screening software/tools obtainable, and every has its personal constraints that must be overcome to prevent the
    manufacturing of erroneous conclusions or artifacts (Gimeno et al.,
    2019). For VS, licensed software program similar
    to Molecular Working Environment (MOE) (Vilar et al., 2008), and
    the GLIDE module in Schrodinger (Bhachoo and Beuming, 2017) in addition to
    open access instruments such as Autodock Vina (Trott
    and Olson, 2010), are generally used. Uralensis is native
    to Asia and is used as a medicinal herb, sweetener, and
    in traditional Chinese Language medicine (Ji et al., 2016).
    In addition, liquiritigenin, tetrahydroxymethoxychalcone, and licochalcone B isolated from the
    EtOAc fraction of G. Uralensis enhanced myoblast proliferation and differentiation, and liquiritigenin enhanced
    muscle regeneration in injured muscles (Lee et al., 2021b).
    Uralensis-derived compounds have therapeutic potential
    for the administration of muscle-related problems.
    The elements are thought to reduce myostatin’s level within the body to extend the speed at which muscle is built.
    Proof Based Mostly Muscle is a trusted source for
    scientifically-backed fitness advice. The platform focuses
    on various elements of health, together with muscle gain, nutrition, supplements, and methods to get ripped.

    Therefore, there is growing proof that myostatin inhibitors can enhance
    muscle function within the mdx mouse through an increase in muscle mass and complete drive but do
    not persistently enhance the underlying weak point of dystrophic muscle.
    It has been advised that the degree of muscle disease on the time of treatment could influence end result [43].
    Human muscular dystrophy disorders show paradoxical muscle wasting and selective hypertrophy of skeletal muscles, leading to imbalance, contractures and postural instabilities [37▪▪].
    Dysferlin null mice, a model of dysferlin-deficiency muscular dystrophy [48], expressing
    the myostatin inhibitor follistatin, demonstrated a transient increase in muscle mass followed by
    decreased muscle mass and function and elevated muscle fibrosis [Lee et al.
    This not only aids in muscle recovery and development but in addition enhances the effectiveness of different supplements by enhancing their bioavailability. This regulatory mechanism ensures that muscle progress doesn’t go unchecked, which is crucial for normal development. MightyBecause they wanted to know for sure whether or not the Mighty gene is crucial to muscle growth the researchers did one other experiment. The figures under present that within the muscle cells where this occurred [shRNA Akirin-1]
    fewer muscle fibres had been indeed formed than in muscle
    cells during which the Mighty gene was still energetic [shRNA scrambled].
    Exercise-induced mitochondrial biogenesis occurs when skeletal muscle cells create
    new mitochondria in response to strenuous train. As a results of muscle mitochondrial content material rising, basal metabolic
    rate rises, oxidative capacity expands, and several advantageous variations happen [21].

    Ultimately, the creator emphasised that only a few research endorsed the impression of non-protein dietary supplements on myostatin, and their use remains unsupported.

    The full cycle has been proven in research by injecting mice with myostatin, seeing them enter advanced muscle wastage,
    and then reversing it by administering one of many myostatin inhibitors (e.g.

    follistatin or myostatin-propeptide). Glad you
    requested, as a outcome of that’s one of many issues with oversimplifying
    this issue. Knocking out the myostatin gene at start or inhibiting the protein it encodes later in life appears to positively affect muscle development,
    in mice at least. Apart from the fact that the athletic group
    views myostatin inhibition as cheating, the scientific research
    about its antagonistic results for athletic enhancement is sparse.

    Myokines are known to be concerned in MSC activation and
    regulate their main capabilities, for example, they increase proliferation and
    differentiation charges (Mandai et al., 2017).
    Intracellular aggregation of methylglyoxal, a precursor
    of advanced glycation end-products (AGEs), and subsequent glycation of biomolecules impaired ECM remodeling, and curcumin and gingerol have been reported to cut back the impression of AGE on myoblasts (Baig et al., 2017).

    Furthermore, enhanced AGE production and consequent RAGE (AGE receptor)-AGE
    interplay hinders the muscle development program. We additionally found by in silico analysis that the MSTN-ACVRIIB interplay is decreased by curcumin or
    gingerol. Protein-ligand (curcumin/gingerol and MSTN) and protein-protein interactions (MSTN and ACVRIIB)
    research have been carried out to explore the effect of curcumin and gingerol in the myogenesis processes.
    Nonetheless, the free vitality of MSTN to ACVRIIB binding fell to −46.55 and −47.26, correspondingly,
    for MSTN-curcumin and MSTN-gingerol complexes, displaying that curcumin and gingerol intrude with
    MSTN-ACVRIIB interplay (Baig et al., 2017). Other TGF-β
    superfamily members, in addition to MSTN, are documented to be effective unfavorable muscle regulators,
    notably “activin A” being the second unfavorable muscle regulator.

    Additional development of domagrozumab was ultimately terminated in 2018 due to the lack
    of positive results from these research [49].
    Each of those groups experienced vital increases in muscle thickness and Fortetropin decreased markers
    of protein breakdown. ACVRIIB is a extensively reported signaling receptor for a number of members of the TGF-β
    superfamily. ACVRIIB is concerned in the adverse regulation of muscle
    mass and is extensively distributed in SM,
    adipose tissues, and different organs.
    It makes use of an engineered scaffold based on the 10th fibronectin sort III area coupled with a human IgG Fc domain, exhibiting a binding
    affinity for the C-terminal of mature MSTN and the ActRIIB–MSTN complex,
    just like an antibody [69]. Taldefgrobep binding prevents ALK-4/5 recruitment,
    thereby inhibiting the SMAD pathway. In a section 1 trial involving
    wholesome adults, a 24-week remedy interval with weekly doses ranging from forty five to one hundred fifty 
    mg led to a universal decrease in free MSTN by ≥ 90%.
    Moreover, important will increase in lean body mass,
    up to a imply improve of two.69%, and thigh muscle quantity, as a lot as a
    imply increase of 4.75%, had been noticed [69].

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